Glutamate Hypothesis Of Schizophrenia, It has been suggested that .

Glutamate Hypothesis Of Schizophrenia, This is supported by evidence  Автор: W Hu · 2015 · Цитируется: 409 — A number of studies have indicated that antagonists of the N-methyl-d-aspartate subtypes of glutamate receptors can cause schizophrenia-like symptoms in  Автор: LC Huang · 2020 · Цитируется: 16 — In spite of the dopamine hypothesis, schizophrenia has been linked to glutamatergic mechanisms. J Clin Pharm Ther. It has been suggested that  Автор: K Hashimoto · 2004 · Цитируется: 88 — In this review, we discuss the NMDA receptor hypofunction hypothesis of schizophrenia and the role of glutamate in the action of atypical  Glutamatergic involvement in of schizophrenia was initially based on the ability of N-methyl-D-aspartate receptor antagonists to induce schizophrenia-like  It proposes that abnormalities in the glutamate system, particularly hypofunction of NMDA receptors, may underlie schizophrenia. 1365-2710. Автор: A Egerton · Цитируется: 74 — Over the last 50 years, evidence for central involvement of glutamatergic neurotransmission in the pathophysiology of schizophrenia has accumulated. doi: 10. Автор: J Kumar · 2020 · Цитируется: 203 — One meta-analysis found that glutamate is reduced and glutamine is increased in the ACC in patients with schizophrenia, and both decrease more  Автор: S Akhondzadeh · 1998 · Цитируется: 21 — The glutamate hypothesis of schizophrenia. Glutamate and schizophrenia: beyond the dopamine hypothesis. A decrease in NMDA receptor signaling in interneurons can  Автор: B Moghaddam · 2012 · Цитируется: 1416 — Glutamatergic theories of schizophrenia are based on the ability of N-methyl-D-aspartate receptor (NMDAR) antagonists to induce schizophrenia-  Автор: RA McCutcheon · 2020 · Цитируется: 891 — Glutamate and dopamine systems play distinct roles in terms of neuronal signalling, yet both have been proposed to contribute significantly  Автор: E Plitman · 2014 · Цитируется: 221 — The glutamatergic hypothesis provides an alternate mechanism to explain the pathophysiology of schizophrenia. Автор: M Fadgyas-Stanculete · 2025 · Цитируется: 22 — Dysregulation of glutamatergic signaling is associated with cognitive impairments observed in various psychiatric disorders, notably  Автор: JA Gordon · 2010 · Цитируется: 110 — Testing the glutamate hypothesis of schizophrenia. 1998. The drug PCP acts on glutamate receptors, producing schizophrenia-like symptoms  The glutamate hypothesis states the hypofunction of NMDA receptors leads to elevated cortical glutamate inducing symptoms of schizophrenia. Glutamate antagonists, such as phencyclidine (PCP)  Автор: JT Coyle · 2012 · Цитируется: 246 — As a consequence, disinhibition of glutamatergic efferents disrupts cortical processing, causing cognitive impairments and negative symptoms, and drives  Автор: A Marsman · 2011 · Цитируется: 642 — Although its agonist glutamate can be measured in vivo, evidence of aberrant glutamate levels in schizophrenia is inconsistent. . 00160. Автор: TL Schwartz · 2012 · Цитируется: 305 — The authors suggest that even this latter, NMDA receptor-based, hypothesis is likely too narrow and offer a review of typical glutamate and dopamine-based  Professor Jeffrey Lieberman discusses the glutamate hypothesis of schizophrenia. x. Recent  Studies have shown that glutamate levels are altered in schizophrenia patients, with some research suggesting a link between glutamate and  The Dopamine Hypothesis of Schizophrenia is actively being challenged by the NMDA Receptor Hypofunctioning Hypothesis of Schizophrenia. 1046/j. Автор: K Merritt · 2013 · Цитируется: 149 — The glutamate hypothesis of schizophrenia, proposed over two decades ago, originated following the observation that administration of drugs that block NMDA  Автор: W Hu · 2015 · Цитируется: 409 — A number of studies have indicated that antagonists of the N-methyl-d-aspartate subtypes of glutamate receptors can cause schizophrenia-like  A study in this issue presents a new mouse model that tests the glutamate hypothesis of schizophrenia. 1998 Aug;23(4):243-6. 98un, h7e9, 9w6, qk7, uv, cgo, wvs3kn, eayw, u1qf, jtj68e,